Services · Study Start-up & Site Support

Getting Your Trial
Ready to Enrol

From study start-up and regulatory permits to vendor assessments, source data and SOP development, Alpha CR Solutions prepares your sites and study documentation so the first patient can be screened without delay.

Site Activation
Regulatory & ethics pack
Site contract & budget
Vendors qualified
Source docs & SOPs
Site initiation visit
First patient readySite live

A Strong Start
Protects the Whole Trial

The study start-up phase sets the foundation for everything that follows. Delays in regulatory permits, gaps in vendor qualification, or poorly designed source documents create problems that compound throughout the trial.

Alpha CR Solutions manages the full start-up workstream so that your sites are properly contracted, your documentation is compliant, and your vendors are qualified before the study goes live. We support both naive sites running their first trials and established sites expanding their capacity.

Our engineering-informed, systematic approach means nothing is left to chance, and every essential document is in place before site activation.

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Start-up Checklist

  • Study start-up coordination
  • MTA, import & export permit applications
  • Vendor assessments & qualification
  • Vendor database management
  • Source data template generation
  • Source data review processes
  • SOP development & tracking
  • Site set-up for naive sites
  • Investigator Site File (ISF) build-up
  • Vendor contract support

Start-up & Site
Support Services

A complete set of services to take your trial from protocol to an activated, inspection-ready site.

Study Start-up Services

End-to-end coordination of all start-up activities — from feasibility and site selection through contract execution, regulatory submissions and site activation.

  • Feasibility and site selection support
  • Start-up timeline planning and tracking
  • Essential document collection
  • Site activation coordination

MTA, Import & Export Permits

Preparation and submission of Material Transfer Agreements and the import and export permit applications required to move samples and investigational products.

  • Material Transfer Agreement (MTA) preparation
  • Import permit applications
  • Export permit applications
  • Sample shipment documentation support

Vendor Assessments

Vendor qualification and assessment conducted to your specification, supported by a maintained vendor database for fast, repeatable vendor selection.

  • Vendor qualification per client specification
  • Vendor assessment documentation
  • Maintained vendor database
  • Vendor contract support

Source Data Templates

Generation and review of compliant source data templates before first patient screening — reducing downstream queries and protecting data integrity from day one.

  • Source data template generation
  • Protocol-specific source document design
  • Source data review and gap analysis
  • ALCOA-C aligned documentation

SOP Development & Tracking

Development of Standard Operating Procedures tailored to your site or organisation, with ongoing support and version tracking to keep them current and audit-ready.

  • SOP development and authoring
  • SOP review and gap analysis
  • Version control and tracking
  • Ongoing SOP maintenance support

Site Set-up & ISF Build-up

Hands-on support for naive and established sites — setting up the site, building the Investigator Site File, and coordinating vendor contracts ahead of activation.

  • Naive site set-up and onboarding
  • Established site capacity support
  • Investigator Site File (ISF) build-up
  • Vendor contract coordination

Supporting Naive Sites
Into Their First Trial

Many capable clinical facilities never host trials simply because the start-up burden is too high. Alpha CR Solutions changes that by guiding naive sites through every requirement of their first study.

From building the Investigator Site File to setting up source documents, negotiating vendor contracts and preparing for the site initiation visit, we make sure new sites are genuinely ready, not just nominally activated.

Set Up Your Site

What Site Set-up Includes

  • ISF structure & build
  • Essential documents
  • Source doc templates
  • Vendor contracts
  • Delegation logs
  • Regulatory binders
  • SIV preparation
  • GCP readiness

Starting a new trial or activating a site?

Let Alpha CR Solutions handle the start-up complexity so your site is ready to enrol on time.

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